STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)    
Predicted Functional Partners:
ACO2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.985
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
  
 0.984
GLUD1
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.982
OGDHL
Oxoglutarate dehydrogenase like.
   
 
 0.978
OGDH
Oxoglutarate dehydrogenase.
   
 
 0.978
IDH3A
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.968
IDH3G
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.958
CS
Citrate synthase; Belongs to the citrate synthase family.
  
 0.944
IDH2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 
0.923
GOT2
Aspartate aminotransferase.
   
 0.914
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.