BCCIP protein (Sarcophilus harrisii) - STRING interaction network

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Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCCIP	BRIX1	ENSSHAP00000012372	ENSSHAP00000012614	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Biogenesis of ribosomes BRX1.	0.790
BCCIP	CDKN1A	ENSSHAP00000012372	ENSSHAP00000013540	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Cyclin dependent kinase inhibitor 1A.	0.844
BCCIP	DHX32	ENSSHAP00000012372	ENSSHAP00000012419	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	DEAH-box helicase 32 (putative).	0.781
BCCIP	EIF6	ENSSHAP00000012372	ENSSHAP00000021663	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.898
BCCIP	G3VP01_SARHA	ENSSHAP00000012372	ENSSHAP00000004906	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Uncharacterized protein.	0.872
BCCIP	NIFK	ENSSHAP00000012372	ENSSHAP00000013784	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	RRM domain-containing protein.	0.789
BCCIP	RPF2	ENSSHAP00000012372	ENSSHAP00000002498	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Ribosome production factor 2 homolog.	0.815
BCCIP	RPL23	ENSSHAP00000012372	ENSSHAP00000020275	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.	0.929
BCCIP	TENT5A	ENSSHAP00000012372	ENSSHAP00000007511	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Terminal nucleotidyltransferase 5A.	0.856
BCCIP	TP53	ENSSHAP00000012372	ENSSHAP00000018268	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.792
BRIX1	BCCIP	ENSSHAP00000012614	ENSSHAP00000012372	Biogenesis of ribosomes BRX1.	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	0.790
BRIX1	DHX32	ENSSHAP00000012614	ENSSHAP00000012419	Biogenesis of ribosomes BRX1.	DEAH-box helicase 32 (putative).	0.565
BRIX1	EIF6	ENSSHAP00000012614	ENSSHAP00000021663	Biogenesis of ribosomes BRX1.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]	0.832
BRIX1	G3VP01_SARHA	ENSSHAP00000012614	ENSSHAP00000004906	Biogenesis of ribosomes BRX1.	Uncharacterized protein.	0.995
BRIX1	NIFK	ENSSHAP00000012614	ENSSHAP00000013784	Biogenesis of ribosomes BRX1.	RRM domain-containing protein.	0.984
BRIX1	RPF2	ENSSHAP00000012614	ENSSHAP00000002498	Biogenesis of ribosomes BRX1.	Ribosome production factor 2 homolog.	0.987
BRIX1	RPL23	ENSSHAP00000012614	ENSSHAP00000020275	Biogenesis of ribosomes BRX1.	Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.	0.778
CDKN1A	BCCIP	ENSSHAP00000013540	ENSSHAP00000012372	Cyclin dependent kinase inhibitor 1A.	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	0.844
CDKN1A	TP53	ENSSHAP00000013540	ENSSHAP00000018268	Cyclin dependent kinase inhibitor 1A.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.997
DHX32	BCCIP	ENSSHAP00000012419	ENSSHAP00000012372	DEAH-box helicase 32 (putative).	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.	0.781