MAPK3 protein (Sarcophilus harrisii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF2	ESR1	ENSSHAP00000012784	ENSSHAP00000017952	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.723
ATF2	MAPK3	ENSSHAP00000012784	ENSSHAP00000012745	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.951
DUSP9	MAPK3	ENSSHAP00000009079	ENSSHAP00000012745	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.937
ESR1	ATF2	ENSSHAP00000017952	ENSSHAP00000012784	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.723
ESR1	MAPK3	ENSSHAP00000017952	ENSSHAP00000012745	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Mitogen-activated protein kinase.	0.929
ESR1	RPS6KA1	ENSSHAP00000017952	ENSSHAP00000014515	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Non-specific serine/threonine protein kinase.	0.906
ESR1	RPS6KA2	ENSSHAP00000017952	ENSSHAP00000007360	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Ribosomal protein S6 kinase.	0.890
ESR1	RPS6KA3	ENSSHAP00000017952	ENSSHAP00000011977	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Ribosomal protein S6 kinase.	0.900
ESR1	TP53	ENSSHAP00000017952	ENSSHAP00000018268	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.953
G3W869_SARHA	MAPK3	ENSSHAP00000011624	ENSSHAP00000012745	Uncharacterized protein.	Mitogen-activated protein kinase.	0.951
G3W869_SARHA	PTPN7	ENSSHAP00000011624	ENSSHAP00000014224	Uncharacterized protein.	Protein tyrosine phosphatase non-receptor type 7.	0.879
MAP2K2	MAPK3	ENSSHAP00000010727	ENSSHAP00000012745	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.947
MAPK3	ATF2	ENSSHAP00000012745	ENSSHAP00000012784	Mitogen-activated protein kinase.	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.	0.951
MAPK3	DUSP9	ENSSHAP00000012745	ENSSHAP00000009079	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.937
MAPK3	ESR1	ENSSHAP00000012745	ENSSHAP00000017952	Mitogen-activated protein kinase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.929
MAPK3	G3W869_SARHA	ENSSHAP00000012745	ENSSHAP00000011624	Mitogen-activated protein kinase.	Uncharacterized protein.	0.951
MAPK3	MAP2K2	ENSSHAP00000012745	ENSSHAP00000010727	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.947
MAPK3	PTPN7	ENSSHAP00000012745	ENSSHAP00000014224	Mitogen-activated protein kinase.	Protein tyrosine phosphatase non-receptor type 7.	0.952
MAPK3	RPS6KA1	ENSSHAP00000012745	ENSSHAP00000014515	Mitogen-activated protein kinase.	Non-specific serine/threonine protein kinase.	0.958
MAPK3	RPS6KA2	ENSSHAP00000012745	ENSSHAP00000007360	Mitogen-activated protein kinase.	Ribosomal protein S6 kinase.	0.954