STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE2Prickle planar cell polarity protein 2. (856 aa)    
Predicted Functional Partners:
VANGL2
Vang-like protein.
    
 0.979
DVL3
Uncharacterized protein.
    
 0.976
VANGL1
Vang-like protein.
    
 0.973
DVL2
Dishevelled segment polarity protein 2.
    
 0.963
PRICKLE1
Prickle planar cell polarity protein 1.
    
 
0.906
PRICKLE3
Uncharacterized protein.
  
  
 
0.901
ANKRD6
Ankyrin repeat domain 6.
   
 0.604
FZD6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.543
OPN3
Opsin 3; Belongs to the G-protein coupled receptor 1 family.
      
 0.532
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.
   
 0.530
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.