STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROCK1Uncharacterized protein. (516 aa)    
Predicted Functional Partners:
RHOA
Uncharacterized protein.
   
 0.953
PPP1R12B
Protein phosphatase 1 regulatory subunit.
   
 0.932
CTNNB1
Catenin beta 1.
    
 0.929
MYL9
Myosin light chain 9.
    
 0.929
MYL12B
Myosin light chain 12B.
    
 0.929
MYL7
Myosin light chain 7.
    
 0.925
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
   
 0.921
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle.
    
 0.917
MAPK1
Mitogen-activated protein kinase.
   
 0.917
MAPK3
Mitogen-activated protein kinase.
   
 0.917
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.