TNFRSF11B protein (Sarcophilus harrisii) - STRING interaction network

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Score

TNFRSF11B

Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)

Predicted Functional Partners:

TNFSF11

0.997

CD40LG

0.726

TNFSF15

0.665

TNFSF14

0.642

G3WSF7_SARHA

0.525

TGFB2

0.517

LTB

0.504

LTA

0.485

TNF

0.431

G3VN57_SARHA

0.425

Your Current Organism:

Sarcophilus harrisii

NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40LG	G3WSF7_SARHA	ENSSHAP00000009115	ENSSHAP00000018362	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.490
CD40LG	LTA	ENSSHAP00000009115	ENSSHAP00000004470	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	0.598
CD40LG	LTB	ENSSHAP00000009115	ENSSHAP00000004721	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Lymphotoxin beta; Belongs to the tumor necrosis factor family.	0.506
CD40LG	TNF	ENSSHAP00000009115	ENSSHAP00000004546	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.496
CD40LG	TNFRSF11B	ENSSHAP00000009115	ENSSHAP00000018745	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.	0.726
CD40LG	TNFSF11	ENSSHAP00000009115	ENSSHAP00000001456	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.521
CD40LG	TNFSF14	ENSSHAP00000009115	ENSSHAP00000003575	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF superfamily member 14.	0.487
G3VN57_SARHA	TNFRSF11B	ENSSHAP00000004612	ENSSHAP00000018745	Metallophos domain-containing protein.	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.	0.425
G3VN57_SARHA	TNFSF11	ENSSHAP00000004612	ENSSHAP00000001456	Metallophos domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.619
G3WSF7_SARHA	CD40LG	ENSSHAP00000018362	ENSSHAP00000009115	Uncharacterized protein.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.490
G3WSF7_SARHA	TNFRSF11B	ENSSHAP00000018362	ENSSHAP00000018745	Uncharacterized protein.	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.	0.525
G3WSF7_SARHA	TNFSF11	ENSSHAP00000018362	ENSSHAP00000001456	Uncharacterized protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.981
G3WSF7_SARHA	TNFSF14	ENSSHAP00000018362	ENSSHAP00000003575	Uncharacterized protein.	TNF superfamily member 14.	0.454
LTA	CD40LG	ENSSHAP00000004470	ENSSHAP00000009115	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.598
LTA	LTB	ENSSHAP00000004470	ENSSHAP00000004721	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	Lymphotoxin beta; Belongs to the tumor necrosis factor family.	0.997
LTA	TNF	ENSSHAP00000004470	ENSSHAP00000004546	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.906
LTA	TNFRSF11B	ENSSHAP00000004470	ENSSHAP00000018745	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.	0.485
LTA	TNFSF11	ENSSHAP00000004470	ENSSHAP00000001456	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.557
LTA	TNFSF14	ENSSHAP00000004470	ENSSHAP00000003575	Lymphotoxin alpha; Belongs to the tumor necrosis factor family.	TNF superfamily member 14.	0.442
LTB	CD40LG	ENSSHAP00000004721	ENSSHAP00000009115	Lymphotoxin beta; Belongs to the tumor necrosis factor family.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.506

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