STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOSFos proto-oncogene, AP-1 transcription factor subunit. (450 aa)    
Predicted Functional Partners:
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.979
MAPK10
Mitogen-activated protein kinase.
    
 0.968
MAPK9
Mitogen-activated protein kinase.
    
 0.968
MAPK1
Mitogen-activated protein kinase.
   
 0.968
MAPK3
Mitogen-activated protein kinase.
   
 0.968
MAPK8
Mitogen-activated protein kinase.
    
 0.968
ESR2
Estrogen receptor 2.
    
 0.957
MAPK13
Mitogen-activated protein kinase.
   
 0.955
FOSL1
FOS like 1, AP-1 transcription factor subunit.
     
0.951
SRC
Tyrosine-protein kinase.
   
 0.941
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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