Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (509 aa)    
Predicted Functional Partners:
EU95_0863
Cobalamin biosynthesis protein CbiG; Alternative locus ID: PMIT9201_0686; Cobalt-precorrin-3b C17-methyltransferase.
  
 0.998
EU95_1633
Cobalt-precorrin-8x methylmutase; Alternative locus ID: PMIT9201_1064.
 
 0.995
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.986
EU95_1384
Cob(I)alamin adenosyltransferase; Alternative locus ID: PMIT9201_1275.
 
  
 0.974
EU95_0118
Cobalt-precorrin-4 C11-methyltransferase; Alternative locus ID: PMIT9201_1814; Belongs to the precorrin methyltransferase family.
 
 
 0.968
EU95_0677
Cobalt-precorrin-2 C20-methyltransferase; Alternative locus ID: PMIT9201_1556; Belongs to the precorrin methyltransferase family.
 
  
 0.962
EU95_1365
Cobalt-precorrin-6x reductase; Alternative locus ID: PMIT9201_1256.
 
  
 0.962
EU95_1507
Cobyrinic acid A; Alternative locus ID: PMIT9201_1510; C-diamide synthase.
  
 0.960
EU95_1798
L-threonine 3-O-phosphate decarboxylase; Alternative locus ID: PMIT9201_0130.
 
 0.955
cbiD
Cobalt-precorrin-6 synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.950
Your Current Organism:
Prochlorococcus marinus MIT9201
NCBI taxonomy Id: 93057
Other names: P. marinus str. MIT 9201, Prochlorococcus marinus str. MIT 9201, Prochlorococcus sp. MIT 9201, Prochlorococcus sp. MIT9201
Server load: low (28%) [HD]