| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EU95_0154 | hemF | EU95_0154 | EU95_0806 | tRNA (cytosine34-2'-O-)-methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | 0.715 |
| EU95_0175 | EU95_0487 | EU95_0175 | EU95_0487 | Protoporphyrinogen IX oxidase; Alternative locus ID: PMIT9201_0850; oxygen-independent, HemG. | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.612 |
| EU95_0175 | hemF | EU95_0175 | EU95_0806 | Protoporphyrinogen IX oxidase; Alternative locus ID: PMIT9201_0850; oxygen-independent, HemG. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | 0.847 |
| EU95_0175 | hemH | EU95_0175 | EU95_1386 | Protoporphyrinogen IX oxidase; Alternative locus ID: PMIT9201_0850; oxygen-independent, HemG. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.848 |
| EU95_0487 | EU95_0175 | EU95_0487 | EU95_0175 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protoporphyrinogen IX oxidase; Alternative locus ID: PMIT9201_0850; oxygen-independent, HemG. | 0.612 |
| EU95_0487 | EU95_1676 | EU95_0487 | EU95_1676 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protein-N(5)-glutamine methyltransferase PrmC; Alternative locus ID: PMIT9201_0008; methylates polypeptide chain release factors RF1 and RF2. | 0.705 |
| EU95_0487 | EU95_1781 | EU95_0487 | EU95_1781 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Porphobilinogen synthase; Alternative locus ID: PMIT9201_0113; Belongs to the ALAD family. | 0.451 |
| EU95_0487 | hemC | EU95_0487 | EU95_1357 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.496 |
| EU95_0487 | hemE | EU95_0487 | EU95_1444 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.937 |
| EU95_0487 | hemF | EU95_0487 | EU95_0806 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | 0.757 |
| EU95_0487 | hemH | EU95_0487 | EU95_1386 | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.591 |
| EU95_0809 | hemF | EU95_0809 | EU95_0806 | Signal transduction histidine kinase; Alternative locus ID: PMIT9201_0632. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | 0.659 |
| EU95_0809 | hemH | EU95_0809 | EU95_1386 | Signal transduction histidine kinase; Alternative locus ID: PMIT9201_0632. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.432 |
| EU95_1281 | hemF | EU95_1281 | EU95_0806 | Isochorismatase; Alternative locus ID: PMIT9201_1391. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | 0.744 |
| EU95_1676 | EU95_0487 | EU95_1676 | EU95_0487 | Protein-N(5)-glutamine methyltransferase PrmC; Alternative locus ID: PMIT9201_0008; methylates polypeptide chain release factors RF1 and RF2. | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.705 |
| EU95_1676 | hemF | EU95_1676 | EU95_0806 | Protein-N(5)-glutamine methyltransferase PrmC; Alternative locus ID: PMIT9201_0008; methylates polypeptide chain release factors RF1 and RF2. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. | 0.829 |
| EU95_1676 | hemH | EU95_1676 | EU95_1386 | Protein-N(5)-glutamine methyltransferase PrmC; Alternative locus ID: PMIT9201_0008; methylates polypeptide chain release factors RF1 and RF2. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.829 |
| EU95_1781 | EU95_0487 | EU95_1781 | EU95_0487 | Porphobilinogen synthase; Alternative locus ID: PMIT9201_0113; Belongs to the ALAD family. | Putative coproporphyrinogen III oxidase of BS HemN-type; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.451 |
| EU95_1781 | hemC | EU95_1781 | EU95_1357 | Porphobilinogen synthase; Alternative locus ID: PMIT9201_0113; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| EU95_1781 | hemE | EU95_1781 | EU95_1444 | Porphobilinogen synthase; Alternative locus ID: PMIT9201_0113; Belongs to the ALAD family. | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.844 |