Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)    
Predicted Functional Partners:
EU95_1835
Citrate synthase (si); Alternative locus ID: PMIT9201_0167; Belongs to the citrate synthase family.
   
 0.979
EU95_1900
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
  0.925
mqo
Malate:quinone oxidoreductase; Alternative locus ID: PMIT9201_1682.
    
 0.924
EU95_1084
Aspartate aminotransferase; Alternative locus ID: PMIT9201_1121.
    
 0.910
argH
Argininosuccinate lyase; Alternative locus ID: PMIT9201_0332.
   
 
 0.904
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.892
EU95_0760
Aldehyde dehydrogenase; Alternative locus ID: PMIT9201_1639; Belongs to the aldehyde dehydrogenase family.
   
 0.868
EU95_0923
Adenylosuccinate lyase; Alternative locus ID: PMIT9201_0746; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
0.836
atpA
ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.786
EU95_0226
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.747
Your Current Organism:
Prochlorococcus marinus MIT9201
NCBI taxonomy Id: 93057
Other names: P. marinus str. MIT 9201, Prochlorococcus marinus str. MIT 9201, Prochlorococcus sp. MIT 9201, Prochlorococcus sp. MIT9201
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