| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EU95_0925 | EU95_0926 | EU95_0925 | EU95_0926 | Nitrogen regulatory protein P-II; Alternative locus ID: PMIT9201_0748; Belongs to the P(II) protein family. | Hypothetical protein; Alternative locus ID: PMIT9201_0749; FIG00940849: hypothetical protein. | 0.766 |
| EU95_0925 | queF | EU95_0925 | EU95_0927 | Nitrogen regulatory protein P-II; Alternative locus ID: PMIT9201_0748; Belongs to the P(II) protein family. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.582 |
| EU95_0926 | EU95_0925 | EU95_0926 | EU95_0925 | Hypothetical protein; Alternative locus ID: PMIT9201_0749; FIG00940849: hypothetical protein. | Nitrogen regulatory protein P-II; Alternative locus ID: PMIT9201_0748; Belongs to the P(II) protein family. | 0.766 |
| EU95_0926 | queF | EU95_0926 | EU95_0927 | Hypothetical protein; Alternative locus ID: PMIT9201_0749; FIG00940849: hypothetical protein. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.615 |
| EU95_1440 | EU95_1892 | EU95_1440 | EU95_1892 | Queuosine biosynthesis QueD; Alternative locus ID: PMIT9201_1331; PTPS-I. | 6-pyruvoyl tetrahydrobiopterin synthase; Alternative locus ID: PMIT9201_0224. | 0.892 |
| EU95_1440 | queC | EU95_1440 | EU95_1586 | Queuosine biosynthesis QueD; Alternative locus ID: PMIT9201_1331; PTPS-I. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.832 |
| EU95_1440 | queE | EU95_1440 | EU95_1587 | Queuosine biosynthesis QueD; Alternative locus ID: PMIT9201_1331; PTPS-I. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.979 |
| EU95_1440 | queF | EU95_1440 | EU95_0927 | Queuosine biosynthesis QueD; Alternative locus ID: PMIT9201_1331; PTPS-I. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.826 |
| EU95_1554 | queA | EU95_1554 | EU95_0054 | Epoxyqueuosine (oQ) reductase QueG; Alternative locus ID: PMIT9201_0985. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.970 |
| EU95_1554 | queC | EU95_1554 | EU95_1586 | Epoxyqueuosine (oQ) reductase QueG; Alternative locus ID: PMIT9201_0985. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.628 |
| EU95_1554 | queE | EU95_1554 | EU95_1587 | Epoxyqueuosine (oQ) reductase QueG; Alternative locus ID: PMIT9201_0985. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.618 |
| EU95_1554 | queF | EU95_1554 | EU95_0927 | Epoxyqueuosine (oQ) reductase QueG; Alternative locus ID: PMIT9201_0985. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.572 |
| EU95_1554 | tgt | EU95_1554 | EU95_1723 | Epoxyqueuosine (oQ) reductase QueG; Alternative locus ID: PMIT9201_0985. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.575 |
| EU95_1892 | EU95_1440 | EU95_1892 | EU95_1440 | 6-pyruvoyl tetrahydrobiopterin synthase; Alternative locus ID: PMIT9201_0224. | Queuosine biosynthesis QueD; Alternative locus ID: PMIT9201_1331; PTPS-I. | 0.892 |
| EU95_1892 | queC | EU95_1892 | EU95_1586 | 6-pyruvoyl tetrahydrobiopterin synthase; Alternative locus ID: PMIT9201_0224. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.832 |
| EU95_1892 | queE | EU95_1892 | EU95_1587 | 6-pyruvoyl tetrahydrobiopterin synthase; Alternative locus ID: PMIT9201_0224. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.982 |
| EU95_1892 | queF | EU95_1892 | EU95_0927 | 6-pyruvoyl tetrahydrobiopterin synthase; Alternative locus ID: PMIT9201_0224. | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.847 |
| queA | EU95_1554 | EU95_0054 | EU95_1554 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Epoxyqueuosine (oQ) reductase QueG; Alternative locus ID: PMIT9201_0985. | 0.970 |
| queA | queC | EU95_0054 | EU95_1586 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.624 |
| queA | queE | EU95_0054 | EU95_1587 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.638 |
