Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EU95_1977Serine--glyoxylate aminotransferase; Alternative locus ID: PMIT9201_0309. (376 aa)    
Predicted Functional Partners:
EU95_0442
D-3-phosphoglycerate dehydrogenase; Alternative locus ID: PMIT9201_0407; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.933
EU95_1376
Phosphoglycerate mutase; Alternative locus ID: PMIT9201_1267; Belongs to the phosphoglycerate mutase family.
    
  0.917
EU95_0171
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.772
EU95_1610
Glycine dehydrogenase (decarboxylating) (glycine cleavage system P protein); Alternative locus ID: PMIT9201_1041; Belongs to the GcvP family.
     
 0.689
EU95_0206
Pyruvate kinase; Alternative locus ID: PMIT9201_0881; Belongs to the pyruvate kinase family.
     
  0.658
EU95_1984
4-hydroxythreonine-4-phosphate dehydrogenase; Alternative locus ID: PMIT9201_0316; Belongs to the PdxA family.
     
  0.656
cbiD
Cobalt-precorrin-6 synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.653
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
  0.601
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.592
EU95_0760
Aldehyde dehydrogenase; Alternative locus ID: PMIT9201_1639; Belongs to the aldehyde dehydrogenase family.
   
 0.581
Your Current Organism:
Prochlorococcus marinus MIT9201
NCBI taxonomy Id: 93057
Other names: P. marinus str. MIT 9201, Prochlorococcus marinus str. MIT 9201, Prochlorococcus sp. MIT 9201, Prochlorococcus sp. MIT9201
Server load: low (10%) [HD]