Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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ABX08238.1Retinal pigment epithelial membrane protein; COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]. (495 aa)    
Predicted Functional Partners:
hisB
COG131 Imidazoleglycerol-phosphate dehydratase [Amino acid transport and metabolism].
       0.634
nnrD
Predicted sugar kinase fused to uncharacterized domain; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydrata [...]
      
 0.583
fabI
COG623 Enoyl-[acyl-carrier-protein].
       0.512
ABX08695.1
COG702 Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].
  
     0.472
ABX08475.1
Light dependent protochlorophyllide oxido-reductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
  
     0.458
pds
Phytoene desaturase; COG3349 Uncharacterized conserved protein [Function unknown].
  
   
 0.447
ABX09686.1
COG596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].
  
     0.444
degT
Putative pleiotropic regulatory protein; COG399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Belongs to the DegT/DnrJ/EryC1 family.
       0.427
ABX08299.1
COG1012 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Belongs to the aldehyde dehydrogenase family.
  
 
 
 0.413
Your Current Organism:
Prochlorococcus marinus MIT9211
NCBI taxonomy Id: 93059
Other names: P. marinus str. MIT 9211, Prochlorococcus marinus str. MIT 9211, Prochlorococcus sp. MIT 9211, Prochlorococcus sp. MIT9211
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