Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptaCOG857 BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]. (363 aa)    
Predicted Functional Partners:
ABX08411.1
Conserved hypothetical protein.
       0.712
ABX08412.1
COG1666 Uncharacterized protein conserved in bacteria [Function unknown]; Belongs to the UPF0234 family.
       0.544
ABX09491.1
COG546 Predicted phosphatases [General function prediction only].
  
    0.524
ABX08409.1
Related to short-chain alcohol dehydrogenases; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only].
  
    0.504
hflC
Band 7 protein; COG330 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].
 
     0.452
ABX08321.1
Conserved hypothetical protein.
  
     0.446
ndhO
Conserved hypothetical protein; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
  
     0.432
pykF
COG469 Pyruvate kinase [Carbohydrate transport and metabolism]; Belongs to the pyruvate kinase family.
  
  
 0.418
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
   
 0.416
ABX08226.1
Conserved hypothetical protein.
  
     0.412
Your Current Organism:
Prochlorococcus marinus MIT9211
NCBI taxonomy Id: 93059
Other names: P. marinus str. MIT 9211, Prochlorococcus marinus str. MIT 9211, Prochlorococcus sp. MIT 9211, Prochlorococcus sp. MIT9211
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