Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amyAGlycoside hydrolase family 13; COG366 Glycosidases [Carbohydrate transport and metabolism]. (578 aa)    
Predicted Functional Partners:
ABX08605.1
Possible Vng0271c.
   
 0.974
ABX08607.1
COG3769 Predicted hydrolase (HAD superfamily) [General function prediction only].
 
   
 0.957
glgP
Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 0.946
malQ
COG1640 4-alpha-glucanotransferase [Carbohydrate transport and metabolism].
  
 
 0.940
glgC
COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
  
 
 0.939
pgm
COG33 Phosphoglucomutase [Carbohydrate transport and metabolism].
    
 0.916
ABX09224.1
Glucose-1-phosphate cytidylyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure an.
     
 0.900
ABX08608.1
COG4240 Predicted kinase [General function prediction only].
 
    0.755
glgX
Putative isoamylase; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.674
gltB
Ferredoxin-dependent glutamate synthase, Fd-GOGAT; COG69 Glutamate synthase domain 2 [Amino acid transport and metabolism].
     
 0.656
Your Current Organism:
Prochlorococcus marinus MIT9211
NCBI taxonomy Id: 93059
Other names: P. marinus str. MIT 9211, Prochlorococcus marinus str. MIT 9211, Prochlorococcus sp. MIT 9211, Prochlorococcus sp. MIT9211
Server load: low (16%) [HD]