| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABX08965.1 | acs | P9211_10341 | P9211_10301 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.557 |
| ABX08965.1 | amiC | P9211_10341 | P9211_10331 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | Cell wall hydrolase/autolysin; COG860 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]. | 0.822 |
| ABX08965.1 | aroA | P9211_10341 | P9211_10371 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.530 |
| ABX08965.1 | comB | P9211_10341 | P9211_10351 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | Probable 2-phosphosulfolactate phosphatase; COG2045 Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Belongs to the ComB family. | 0.761 |
| ABX08965.1 | murI | P9211_10341 | P9211_10321 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | Putative aspartate and glutamate racemases:Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.821 |
| ABX08965.1 | sds | P9211_10341 | P9211_10311 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | Polyprenyl synthetase; COG142 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Belongs to the FPP/GGPP synthase family. | 0.773 |
| ABX08965.1 | ubiD | P9211_10341 | P9211_10361 | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | COG43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Belongs to the UbiD family. | 0.528 |
| ABX08969.1 | amiC | P9211_10381 | P9211_10331 | Hypothetical protein; COG4121 Uncharacterized conserved protein [Function unknown]. | Cell wall hydrolase/autolysin; COG860 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]. | 0.466 |
| ABX08969.1 | aroA | P9211_10381 | P9211_10371 | Hypothetical protein; COG4121 Uncharacterized conserved protein [Function unknown]. | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.512 |
| ABX08969.1 | comB | P9211_10381 | P9211_10351 | Hypothetical protein; COG4121 Uncharacterized conserved protein [Function unknown]. | Probable 2-phosphosulfolactate phosphatase; COG2045 Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Belongs to the ComB family. | 0.444 |
| ABX08969.1 | murI | P9211_10381 | P9211_10321 | Hypothetical protein; COG4121 Uncharacterized conserved protein [Function unknown]. | Putative aspartate and glutamate racemases:Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.480 |
| ABX08969.1 | ubiD | P9211_10381 | P9211_10361 | Hypothetical protein; COG4121 Uncharacterized conserved protein [Function unknown]. | COG43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Belongs to the UbiD family. | 0.419 |
| acs | ABX08965.1 | P9211_10301 | P9211_10341 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | 0.557 |
| acs | amiC | P9211_10301 | P9211_10331 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Cell wall hydrolase/autolysin; COG860 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]. | 0.554 |
| acs | aroA | P9211_10301 | P9211_10371 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.409 |
| acs | comB | P9211_10301 | P9211_10351 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Probable 2-phosphosulfolactate phosphatase; COG2045 Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Belongs to the ComB family. | 0.516 |
| acs | murI | P9211_10301 | P9211_10321 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative aspartate and glutamate racemases:Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.554 |
| acs | sds | P9211_10301 | P9211_10311 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Polyprenyl synthetase; COG142 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Belongs to the FPP/GGPP synthase family. | 0.649 |
| amiC | ABX08965.1 | P9211_10331 | P9211_10341 | Cell wall hydrolase/autolysin; COG860 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]. | Possible nitrilase; COG388 Predicted amidohydrolase [General function prediction only]. | 0.822 |
| amiC | ABX08969.1 | P9211_10331 | P9211_10381 | Cell wall hydrolase/autolysin; COG860 N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]. | Hypothetical protein; COG4121 Uncharacterized conserved protein [Function unknown]. | 0.466 |