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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (237 aa)    
Predicted Functional Partners:
rpe
COG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.952
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 0.945
gnd
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 
 0.939
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.936
pgm
COG33 Phosphoglucomutase [Carbohydrate transport and metabolism].
  
 
 0.924
ABX09079.1
COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism].
    
 0.909
prkB
COG3954 Phosphoribulokinase [Energy production and conversion].
     
 0.900
xylB
Carbohydrate kinase, FGGY family; COG1070 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism].
    
 0.877
ABX09543.1
COG265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones].
       0.734
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
 
      0.703
Your Current Organism:
Prochlorococcus marinus MIT9211
NCBI taxonomy Id: 93059
Other names: P. marinus str. MIT 9211, Prochlorococcus marinus str. MIT 9211, Prochlorococcus sp. MIT 9211, Prochlorococcus sp. MIT9211
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