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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABV51046.1Histidinol phosphatase-like protein; COG241 Histidinol phosphatase and related phosphatases [Amino acid transport and metabolism]. (174 aa)    
Predicted Functional Partners:
ABV51047.1
COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].
 0.998
ABV51048.1
COG2605 Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only].
 
 
 0.996
hisI
COG139 Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.984
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.862
ABV51057.1
COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].
 
 
 0.807
hisC
Aminotransferase class-I; COG79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism].
  
 
 0.801
ABV51049.1
COG1089 GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane].
 
   
 0.780
hisH
Glutamine amidotransferase class-I; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.696
hisF
Imidazole glycerol phosphate synthase subunit HisF (cyclase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.680
hisA
COG106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase [Amino acid transport and metabolism].
  
  
 0.676
Your Current Organism:
Prochlorococcus marinus MIT9215
NCBI taxonomy Id: 93060
Other names: P. marinus str. MIT 9215, Prochlorococcus marinus MIT 9215, Prochlorococcus marinus str. MIT 9215, Prochlorococcus sp. MIT 9215, Prochlorococcus sp. MIT9215
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