Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABD29255.1Lipoprotein, SirC, putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (304 aa)    
Predicted Functional Partners:
ABD29257.1
Periplasmic binding protein, putative.
 
 0.982
ABD29256.1
Lipoprotein, SirB, putative; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 
0.966
ABD29786.1
Iron compound ABC transporter, ATP-binding protein.
 
 
 0.924
ABD29751.1
Iron compound ABC transporter, substrate-binding protein, putative.
 
   0.780
ABD30202.1
Iron compound ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
    0.738
isdE
Conserved hypothetical protein; Involved in heme (porphyrin) scavenging. Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme. Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors to the probable permease IsdF; Belongs to the bacterial solute-binding protein 8 family.
 
   0.644
ABD31453.1
ABC transporter periplasmic binding protein, putative.
 
    0.549
ABD30101.1
Conserved hypothetical protein.
 
    0.526
ABD29881.1
Conserved hypothetical protein.
  
  
 0.517
ABD31286.1
Conserved hypothetical protein.
 
 
 0.507
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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