STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldh1L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate (Potential). Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity). (269 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.972
ABD29594.1
Glutamate synthase, large subunit, putative.
  
 
 0.905
ABD30367.1
Conserved hypothetical protein.
  
 
 0.886
ABD30870.1
Conserved hypothetical protein; Belongs to the citrate synthase family.
  
 0.877
pflB
Formate acetyltransferase; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
   
 
 0.838
pgi
Glucose-6-phosphate isomerase.
  
 
 0.828
ABD30869.1
Isocitrate dehydrogenase, NADP-dependent.
  
 
 0.804
ABD29324.1
Conserved hypothetical protein; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.770
ABD30181.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.747
ABD30878.1
NADP-dependent malic enzyme, putative.
  
 0.740
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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