Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ABD29424.1Conserved hypothetical protein. (219 aa)    
Predicted Functional Partners:
ABD31027.1
ABC transporter, ATP-binding protein, putative.
 
    
0.925
ABD29425.1
Conserved hypothetical protein.
  
    0.884
ABD29426.1
Conserved hypothetical protein.
  
    0.884
nikD
Peptide ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import. Probably responsible for energy coupling to the transport system. Required for full urease activity and plays a significant role in the virulence of S.aureus during urinary tract infection (UTI).
  
     0.726
ABD31200.1
ABC transporter, ATP-binding protein, putative.
 
    
0.688
ABD29427.1
Conserved hypothetical protein.
 
     0.676
metN1
Conserved hypothetical protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
    
0.675
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.564
ABD31823.1
Membrane spanning protein, putative.
  
   0.542
dnaK
DNAk protein, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
   0.445
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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