Conserved hypothetical protein.

Conserved hypothetical protein; Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction. Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12. Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin. Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration.

Conserved hypothetical phage protein; Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses (By similarity). Prevents phagocytosis of the bacterium; Belongs to the CHIPS/FLIPr family.

Conserved hypothetical protein; May be involved in countering the first line of host defense mechanisms. Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 (By similarity); Belongs to the CHIPS/FLIPr family.

Conserved hypothetical phage protein; Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses (By similarity). Prevents phagocytosis of the bacterium; Belongs to the CHIPS/FLIPr family.

Conserved hypothetical protein; Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction. Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12. Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin. Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration.

Conserved hypothetical protein; May be involved in countering the first line of host defense mechanisms. Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 (By similarity); Belongs to the CHIPS/FLIPr family.

Conserved hypothetical phage protein; Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses (By similarity). Prevents phagocytosis of the bacterium; Belongs to the CHIPS/FLIPr family.

Conserved hypothetical protein; May be involved in countering the first line of host defense mechanisms. Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 (By similarity); Belongs to the CHIPS/FLIPr family.

Conserved hypothetical protein; Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction. Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12. Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin. Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration.

Conserved hypothetical protein; Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction. Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12. Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin. Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration.

Conserved hypothetical protein.

Conserved hypothetical protein; Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction. Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12. Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin. Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration.

Conserved hypothetical phage protein; Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses (By similarity). Prevents phagocytosis of the bacterium; Belongs to the CHIPS/FLIPr family.

Conserved hypothetical protein; Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction. Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12. Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin. Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration.

Conserved hypothetical protein; May be involved in countering the first line of host defense mechanisms. Impairs the leukocyte response to FPRL1 agonists by binding directly to host FPRL1 (By similarity); Belongs to the CHIPS/FLIPr family.