STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD29560.1Type I restriction-modification system, M subunit. (490 aa)    
Predicted Functional Partners:
ABD29561.1
Restriction modification system specificity subunit, putative.
 
 
 0.993
ABD29341.1
Type I site-specific deoxyribonuclease, HsdR family, putative; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.983
ABD30995.1
Type I restriction-modification enzyme, S subunit, EcoA family, putative.
 
 0.974
ABD29559.1
Conserved hypothetical protein.
       0.517
ABD30989.1
Conserved hypothetical protein.
      
 0.509
ABD30597.1
Petidoglycan hydrolase, putative; Has weak lytic activity toward S.aureus cells. Full-length protein has no activity, but fusion of the Peptidase C51 domain to the lysostaphin SH3 cell wall binding domain yields an active chimeric enzyme, suggesting that PH may be functional.
      
 0.504
ABD29567.1
Conserved hypothetical protein.
      
 0.491
ABD29906.1
Excinuclease ABC, B subunit.
    
   0.480
ABD29908.1
Excinuclease ABC subunit B, putative; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits d [...]
    
   0.480
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.