Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
metN1Conserved hypothetical protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)    
Predicted Functional Partners:
ABD29585.1
ABC transporter, permease protein, putative.
 
 0.999
ABD29586.1
ABC transporter, substrate-binding protein, putative; Belongs to the nlpA lipoprotein family.
 
 0.996
ABD29969.1
Conserved hypothetical protein.
 
 0.994
ABD29970.1
Conserved hypothetical protein; Belongs to the nlpA lipoprotein family.
 
 0.985
metN2
ABC transporter, ATP-binding protein, putative; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
  
  
0.913
ABD29507.1
Conserved hypothetical protein.
   
  
 0.757
ABD29825.1
Conserved hypothetical protein.
 
    
0.755
ABD29424.1
Conserved hypothetical protein.
 
    
0.675
ABD29773.1
Conserved hypothetical protein.
    
   0.589
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.565
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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