node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABD29647.1 | pdxS | SAOUHSC_00497 | SAOUHSC_00499 | Conserved hypothetical protein. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.688 |
ABD29647.1 | pdxT | SAOUHSC_00497 | SAOUHSC_00500 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.643 |
ABD29709.1 | pdxS | SAOUHSC_00562 | SAOUHSC_00499 | Phosphomethylpyrimidine kinase. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.899 |
ABD29709.1 | pdxT | SAOUHSC_00562 | SAOUHSC_00500 | Phosphomethylpyrimidine kinase. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.893 |
ABD30296.1 | ABD30964.1 | SAOUHSC_01189 | SAOUHSC_01901 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Conserved hypothetical protein. | 0.792 |
ABD30296.1 | guaA | SAOUHSC_01189 | SAOUHSC_00375 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | 0.498 |
ABD30296.1 | pdxS | SAOUHSC_01189 | SAOUHSC_00499 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.435 |
ABD30296.1 | pdxT | SAOUHSC_01189 | SAOUHSC_00500 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.401 |
ABD30296.1 | rbsK | SAOUHSC_01189 | SAOUHSC_00239 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Ribokinase, putative; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.547 |
ABD30964.1 | ABD30296.1 | SAOUHSC_01901 | SAOUHSC_01189 | Conserved hypothetical protein. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.792 |
ABD30964.1 | pdxS | SAOUHSC_01901 | SAOUHSC_00499 | Conserved hypothetical protein. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.893 |
ABD30964.1 | pdxT | SAOUHSC_01901 | SAOUHSC_00500 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.893 |
guaA | ABD30296.1 | SAOUHSC_00375 | SAOUHSC_01189 | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.498 |
guaA | panC | SAOUHSC_00375 | SAOUHSC_02918 | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.582 |
guaA | pdxS | SAOUHSC_00375 | SAOUHSC_00499 | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.449 |
guaA | pdxT | SAOUHSC_00375 | SAOUHSC_00500 | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | Conserved hypothetical protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.433 |
guaA | rbsK | SAOUHSC_00375 | SAOUHSC_00239 | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | Ribokinase, putative; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.755 |
panC | guaA | SAOUHSC_02918 | SAOUHSC_00375 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | GMP synthase, putative; Catalyzes the synthesis of GMP from XMP. | 0.582 |
panC | panD | SAOUHSC_02918 | SAOUHSC_02916 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.999 |
panC | pdxS | SAOUHSC_02918 | SAOUHSC_00499 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.407 |