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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhAlcohol dehydrogenase I, putative. (336 aa)    
Predicted Functional Partners:
ABD29294.1
Alcohol dehydrogenase, iron-containing, putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.988
aldA
Aldehyde dehydrogenase, putative.
 
 
 
 0.956
aldH1
Aldehyde dehydrogenase, putative; Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes the oxidation of 4,4'- diaponeurosporen-4-al to yield 4,4'-diaponeurosporenoic acid. Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.942
ABD31394.1
Aldehyde dehydrogenase, putative.
 
 
 
 0.890
pflB
Formate acetyltransferase; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
   
  
 0.814
ABD29374.1
Conserved hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.753
tdcB
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). Belongs to the serine/thre [...]
   
 
 0.681
ABD29269.1
3-ketoacyl-acyl carrier protein reductase, putative.
  
 
 0.644
ABD31928.1
Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 
 
 0.626
ABD29747.1
Conserved hypothetical protein.
       0.563
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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