STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD29761.1Integrase/recombinase, putative. (186 aa)    
Predicted Functional Partners:
mnhA2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
       0.832
mnhB2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
       0.832
mnhC2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
       0.832
mnhD2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
       0.832
mnhE2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
       0.832
ABD29760.1
Conserved hypothetical protein.
       0.709
mnhG2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
       0.525
topB
DNA topoisomerase III, putative; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus remov [...]
 
  
 0.463
ABD29374.1
Conserved hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 
  0.444
hslV
Heat shock protein HslV, putative; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
    0.439
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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