Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tarAConserved hypothetical protein; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid; Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily. (254 aa)    
Predicted Functional Partners:
ABD29893.1
Conserved hypothetical protein.
 
 
 0.988
tarB
tagB protein, putative; Catalyzes the addition of a single glycerol phosphate residue to the prenoldiphosphate-linked disaccharide. Belongs to the CDP-glycerol glycerophosphotransferase family.
 
 0.959
tagH
Teichoic acid translocation ATP-binding protein, putative; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system.
 
 
 
 0.600
tarK
tagB protein, putative; Can catalyze the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit; Belongs to the CDP-glycerol glycerophosphotransferase family.
 
 
 0.588
tarL
Conserved hypothetical protein; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit. Synthesizes polymers of more than 40 ribitol phosphate units in length; Belongs to the CDP-glycerol glycerophosphotransferase family.
 
 
 0.586
tarD
Glycerol-3-phosphate cytidylyltransferase; Catalyzes the transfer of the cytidylyl group of CTP to sn- glycerol 3-phosphate so the activated glycerol 3-phosphate can be used for teichoic acid synthesis, via incorporation into both the linkage unit by TarB and TarF; Belongs to the cytidylyltransferase family.
  
  
 0.581
tarF
Teichoic acid biosynthesis protein F, putative; Catalyzes the addition of a second glycerol phosphate unit from CDP-glycerol to the prenolpyrophosphate-linked disaccharide, to complete the linkage unit.
 
 
 0.555
ABD29777.1
Teichoic acid biosynthesis protein, putative.
 
   
 0.540
ABD29310.1
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
   
 0.520
ABD31383.1
UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
   
 0.518
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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