Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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tarDGlycerol-3-phosphate cytidylyltransferase; Catalyzes the transfer of the cytidylyl group of CTP to sn- glycerol 3-phosphate so the activated glycerol 3-phosphate can be used for teichoic acid synthesis, via incorporation into both the linkage unit by TarB and TarF; Belongs to the cytidylyltransferase family. (132 aa)    
Predicted Functional Partners:
gpsA
Glycerol-3-phosphate dehydrogenase, NAD-dependent, putative; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
  0.971
tarB
tagB protein, putative; Catalyzes the addition of a single glycerol phosphate residue to the prenoldiphosphate-linked disaccharide. Belongs to the CDP-glycerol glycerophosphotransferase family.
 
  
 0.960
tarF
Teichoic acid biosynthesis protein F, putative; Catalyzes the addition of a second glycerol phosphate unit from CDP-glycerol to the prenolpyrophosphate-linked disaccharide, to complete the linkage unit.
 
  
 0.957
glpD
Conserved hypothetical protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
     
  0.900
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
  0.900
tarK
tagB protein, putative; Can catalyze the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit; Belongs to the CDP-glycerol glycerophosphotransferase family.
 
  
 0.856
tarL
Conserved hypothetical protein; Responsible for the polymerization of the main chain of the major teichoic acid by sequential transfer of ribitol phosphate units from CDP-ribitol to the second glycerol phosphate attached to the disaccharide linkage unit. Synthesizes polymers of more than 40 ribitol phosphate units in length; Belongs to the CDP-glycerol glycerophosphotransferase family.
 
  
 0.856
ABD29777.1
Teichoic acid biosynthesis protein, putative.
 
   
 0.856
ABD31657.1
Conserved hypothetical protein.
 
  
 0.814
tagH
Teichoic acid translocation ATP-binding protein, putative; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system.
 
   
 0.748
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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