node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABD30932.1 | ABD31998.1 | SAOUHSC_01867 | SAOUHSC_03012 | D-amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. | Histidinol-phosphate aminotransferase, putative. | 0.900 |
ABD30932.1 | hisC | SAOUHSC_01867 | SAOUHSC_00733 | D-amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.901 |
ABD30932.1 | hisF | SAOUHSC_01867 | SAOUHSC_03008 | D-amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.703 |
ABD31183.1 | ABD31998.1 | SAOUHSC_02135 | SAOUHSC_03012 | Conserved hypothetical protein. | Histidinol-phosphate aminotransferase, putative. | 0.913 |
ABD31183.1 | hisB | SAOUHSC_02135 | SAOUHSC_03011 | Conserved hypothetical protein. | Imidazoleglycerol-phosphate dehydratase, putative. | 0.512 |
ABD31183.1 | hisC | SAOUHSC_02135 | SAOUHSC_00733 | Conserved hypothetical protein. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.903 |
ABD31183.1 | hisD | SAOUHSC_02135 | SAOUHSC_03013 | Conserved hypothetical protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.406 |
ABD31183.1 | hisF | SAOUHSC_02135 | SAOUHSC_03008 | Conserved hypothetical protein. | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.745 |
ABD31183.1 | tyrA | SAOUHSC_02135 | SAOUHSC_01364 | Conserved hypothetical protein. | Prephenate dehydrogenase, putative; Belongs to the prephenate/arogenate dehydrogenase family. | 0.977 |
ABD31998.1 | ABD30932.1 | SAOUHSC_03012 | SAOUHSC_01867 | Histidinol-phosphate aminotransferase, putative. | D-amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. | 0.900 |
ABD31998.1 | ABD31183.1 | SAOUHSC_03012 | SAOUHSC_02135 | Histidinol-phosphate aminotransferase, putative. | Conserved hypothetical protein. | 0.913 |
ABD31998.1 | hisA | SAOUHSC_03012 | SAOUHSC_03009 | Histidinol-phosphate aminotransferase, putative. | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, putative. | 0.987 |
ABD31998.1 | hisB | SAOUHSC_03012 | SAOUHSC_03011 | Histidinol-phosphate aminotransferase, putative. | Imidazoleglycerol-phosphate dehydratase, putative. | 0.999 |
ABD31998.1 | hisC | SAOUHSC_03012 | SAOUHSC_00733 | Histidinol-phosphate aminotransferase, putative. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.907 |
ABD31998.1 | hisD | SAOUHSC_03012 | SAOUHSC_03013 | Histidinol-phosphate aminotransferase, putative. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.997 |
ABD31998.1 | hisF | SAOUHSC_03012 | SAOUHSC_03008 | Histidinol-phosphate aminotransferase, putative. | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.999 |
ABD31998.1 | hisG | SAOUHSC_03012 | SAOUHSC_03014 | Histidinol-phosphate aminotransferase, putative. | ATP phosphoribosyltransferase, putative; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.985 |
ABD31998.1 | hisH | SAOUHSC_03012 | SAOUHSC_03010 | Histidinol-phosphate aminotransferase, putative. | Imidazole glycerol phosphate synthase, subunit H (hisH), putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.990 |
ABD31998.1 | tyrA | SAOUHSC_03012 | SAOUHSC_01364 | Histidinol-phosphate aminotransferase, putative. | Prephenate dehydrogenase, putative; Belongs to the prephenate/arogenate dehydrogenase family. | 0.958 |
hisA | ABD31998.1 | SAOUHSC_03009 | SAOUHSC_03012 | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase, putative. | Histidinol-phosphate aminotransferase, putative. | 0.987 |