Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
nrdIRibonucleoside-diphosphate reductase 2, putative; Probably involved in ribonucleotide reductase function. (132 aa)    
Predicted Functional Partners:
ABD29876.1
Ribonucleotide-disphosphate reductase beta chain, putative.
 
 
 0.998
ABD29875.1
Ribonucleotide-diphosphate reductase alpha chain, putative; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.996
ABD30151.1
Conserved hypothetical protein.
  
  
 0.880
deoD-2
Purine nucleoside phosphorylase.
      
 0.673
nrdR
Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.557
deoD
Purine nucleoside phosphorylase.
      
 0.554
ABD31935.1
Conserved hypothetical protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
     
 0.554
ABD31936.1
Anaerobic ribonucleoside-triphosphate reductase, putative.
     
 0.547
ABD30535.1
Conserved hypothetical protein.
      
 0.520
mntH
Conserved hypothetical protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
   
  
 0.513
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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