STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepTPeptidase T, putative; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (408 aa)    
Predicted Functional Partners:
ABD29890.1
Conserved hypothetical protein.
       0.846
ABD29891.1
Conserved hypothetical protein.
       0.829
ABD29892.1
Conserved hypothetical protein.
       0.677
glyA
Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.521
ABD30704.1
Proline dipeptidase, putative; Belongs to the peptidase M24B family.
   
 
 0.478
ABD30884.1
Conserved hypothetical protein.
   
 
 0.478
ABD30933.1
Conserved hypothetical protein.
    
 0.474
rocD-2
Ornithine aminotransferase, putative; Catalyzes the interconversion of ornithine to glutamate semialdehyde.
   
 
 0.467
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.464
nixA
High affinity nickel transporter, putative; Secondary nickel transporter. Required for full urease activity; Belongs to the NiCoT transporter (TC 2.A.52) family.
   
  
 0.445
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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