Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABD30020.1Glutamate dehydrogenase, NAD-specific, putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (414 aa)    
Predicted Functional Partners:
ABD29594.1
Glutamate synthase, large subunit, putative.
  
 0.988
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
  
 0.965
ABD30386.1
Glutamine synthetase, type I.
  
 
 0.963
ABD30367.1
Conserved hypothetical protein.
  
 
 0.941
ABD29595.1
NADH-glutamate synthase small subunit, putative.
  
 
 0.934
ABD31298.1
Conserved hypothetical protein.
   
 
 0.932
argJ
Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
     
 0.928
odhA
2-oxoglutarate dehydrogenase, E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
   
 0.913
ABD31692.1
Assimilatory nitrite reductase [NAD(P)H], large subunit, putative; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
 
 0.912
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
  0.904
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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