STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdrCoenzyme A disulfide reductase, putative; Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide. Is also active with other disulfide substrates containing at least one 4'-phosphopantethienyl moiety such as 4,4'- diphosphopantethine, but is not able to reduce oxidized glutathione, cystine, pantethine, or H(2)O(2); Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family. (438 aa)    
Predicted Functional Partners:
ABD29224.1
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
 
 0.992
hisF
Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family.
   
    0.954
ABD29594.1
Glutamate synthase, large subunit, putative.
    
 0.889
ABD31691.1
Assimilatory nitrite reductase [NAD(P)H], small subunit, putative.
  
 0.787
ABD30034.1
Conserved hypothetical protein.
       0.785
ABD30035.1
Conserved hypothetical protein.
    
  0.735
ABD31593.1
Formate dehydrogenase, alpha subunit, putative; In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
  0.688
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
   
    0.643
ABD29225.1
Conserved hypothetical protein.
  
 0.641
rpsE
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
   
   0.611
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.