STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase complex, E1 component, alpha subunit, putative; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (370 aa)    
Predicted Functional Partners:
ABD30161.1
Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase beta subunit, putative.
 0.999
ABD30162.1
Dihydrolipoamide S-acetyltransferase component of pyruvate dehydrogenase complex E2, putative.
 
 0.999
ABD30163.1
Dihydrolipoamide dehydrogenase.
 
 
 0.999
ABD30691.1
2-oxoisovalerate dehydrogenase, E1 component, beta subunit, putative.
 0.998
ABD30693.1
Dihydrolipoamide dehydrogenase.
 
 
 0.982
ABD30690.1
2-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase, putative.
 
 0.947
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.946
odhB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.944
ABD30878.1
NADP-dependent malic enzyme, putative.
   
 
 0.930
ABD30367.1
Conserved hypothetical protein.
     
 0.926
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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