STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD30161.1Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase beta subunit, putative. (325 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase complex, E1 component, alpha subunit, putative; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
ABD30162.1
Dihydrolipoamide S-acetyltransferase component of pyruvate dehydrogenase complex E2, putative.
 
 0.999
ABD30163.1
Dihydrolipoamide dehydrogenase.
 
 0.999
ABD30692.1
2-oxoisovalerate dehydrogenase, E1 component, alpha subunit, putative.
 0.998
ABD30693.1
Dihydrolipoamide dehydrogenase.
 
 0.989
ABD30690.1
2-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase, putative.
 
 0.968
odhB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.955
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.932
ABD30367.1
Conserved hypothetical protein.
   
 
 0.925
prs
Ribose-phosphate pyrophosphokinase, putative; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.918
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.