node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABD30273.1 | ABD31905.1 | SAOUHSC_01165 | SAOUHSC_02909 | Uracil permease, putative. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.943 |
ABD30273.1 | carA | SAOUHSC_01165 | SAOUHSC_01169 | Uracil permease, putative. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.985 |
ABD30273.1 | carB | SAOUHSC_01165 | SAOUHSC_01170 | Uracil permease, putative. | Carbamoyl-phosphate synthase, large subunit. | 0.971 |
ABD30273.1 | pyrB | SAOUHSC_01165 | SAOUHSC_01166 | Uracil permease, putative. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.993 |
ABD30273.1 | pyrC | SAOUHSC_01165 | SAOUHSC_01168 | Uracil permease, putative. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.991 |
ABD30273.1 | pyrE | SAOUHSC_01165 | SAOUHSC_01172 | Uracil permease, putative. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.986 |
ABD30273.1 | pyrF | SAOUHSC_01165 | SAOUHSC_01171 | Uracil permease, putative. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.986 |
ABD30273.1 | pyrR | SAOUHSC_01165 | SAOUHSC_01164 | Uracil permease, putative. | PyrR bifunctional protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.989 |
ABD30273.1 | upp | SAOUHSC_01165 | SAOUHSC_02353 | Uracil permease, putative. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.525 |
ABD31905.1 | ABD30273.1 | SAOUHSC_02909 | SAOUHSC_01165 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uracil permease, putative. | 0.943 |
ABD31905.1 | carA | SAOUHSC_02909 | SAOUHSC_01169 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.984 |
ABD31905.1 | carB | SAOUHSC_02909 | SAOUHSC_01170 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Carbamoyl-phosphate synthase, large subunit. | 0.991 |
ABD31905.1 | pyrB | SAOUHSC_02909 | SAOUHSC_01166 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.992 |
ABD31905.1 | pyrC | SAOUHSC_02909 | SAOUHSC_01168 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
ABD31905.1 | pyrE | SAOUHSC_02909 | SAOUHSC_01172 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |
ABD31905.1 | pyrF | SAOUHSC_02909 | SAOUHSC_01171 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.990 |
ABD31905.1 | pyrR | SAOUHSC_02909 | SAOUHSC_01164 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | PyrR bifunctional protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.864 |
ABD31905.1 | upp | SAOUHSC_02909 | SAOUHSC_02353 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.666 |
carA | ABD30273.1 | SAOUHSC_01169 | SAOUHSC_01165 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil permease, putative. | 0.985 |
carA | ABD31905.1 | SAOUHSC_01169 | SAOUHSC_02909 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.984 |