STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD30354.1Conserved hypothetical protein; Belongs to the FtsK/SpoIIIE/SftA family. (747 aa)    
Predicted Functional Partners:
ABD30355.1
Conserved hypothetical protein.
       0.856
ABD30356.1
Conserved hypothetical protein.
  
    0.811
ABD30357.1
Conserved hypothetical protein.
       0.810
ABD30358.1
Conserved hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.810
ABD30360.1
Conserved hypothetical protein.
 
   
 0.759
ABD29510.1
Chromosome partioning protein, ParB family, putative; Belongs to the ParB family.
  
  
 0.747
ABD32032.1
Conserved hypothetical protein; Belongs to the ParB family.
  
  
 0.718
ABD30359.1
Conserved hypothetical protein.
  
    0.717
rnj2
Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit probably plays a structural rather than enzymatic role as mutation of its putative active site gives no phenotype, and its deletion is partially complemented by inactive RNase J1.
  
    0.686
esxA
Conserved hypothetical protein; Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion (By similarity). Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity (By similarity).
   
 
 0.685
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.