| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABD30379.1 | glpD | SAOUHSC_01279 | SAOUHSC_01278 | Hydrolase, alpha/beta fold family domain protein. | Conserved hypothetical protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.724 |
| ABD30379.1 | hfq | SAOUHSC_01279 | SAOUHSC_01281 | Hydrolase, alpha/beta fold family domain protein. | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.818 |
| ABD30379.1 | miaA | SAOUHSC_01279 | SAOUHSC_01280 | Hydrolase, alpha/beta fold family domain protein. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.834 |
| ABD30559.1 | hfq | SAOUHSC_01474 | SAOUHSC_01281 | Conserved hypothetical protein. | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.707 |
| ABD30559.1 | pnp | SAOUHSC_01474 | SAOUHSC_01251 | Conserved hypothetical protein. | Polyribonucleotide nucleotidyltransferase, putative; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.762 |
| ABD30559.1 | rnr | SAOUHSC_01474 | SAOUHSC_00803 | Conserved hypothetical protein. | Ribonuclease R, putative; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.516 |
| clpX | hfq | SAOUHSC_01778 | SAOUHSC_01281 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.691 |
| clpX | rho | SAOUHSC_01778 | SAOUHSC_02362 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.411 |
| glpD | ABD30379.1 | SAOUHSC_01278 | SAOUHSC_01279 | Conserved hypothetical protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Hydrolase, alpha/beta fold family domain protein. | 0.724 |
| glpD | hfq | SAOUHSC_01278 | SAOUHSC_01281 | Conserved hypothetical protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.768 |
| glpD | miaA | SAOUHSC_01278 | SAOUHSC_01280 | Conserved hypothetical protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.712 |
| hfq | ABD30379.1 | SAOUHSC_01281 | SAOUHSC_01279 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Hydrolase, alpha/beta fold family domain protein. | 0.818 |
| hfq | ABD30559.1 | SAOUHSC_01281 | SAOUHSC_01474 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Conserved hypothetical protein. | 0.707 |
| hfq | clpX | SAOUHSC_01281 | SAOUHSC_01778 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.691 |
| hfq | glpD | SAOUHSC_01281 | SAOUHSC_01278 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Conserved hypothetical protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.768 |
| hfq | katA | SAOUHSC_01281 | SAOUHSC_01327 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Catalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in resistance to paraquat when fur is absent and to tert-butyl hydroperoxide. Is important for survival under glucose starvation and desiccation conditions. Not required for virulence although is necessary for nasal colonization. | 0.789 |
| hfq | miaA | SAOUHSC_01281 | SAOUHSC_01280 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.963 |
| hfq | pnp | SAOUHSC_01281 | SAOUHSC_01251 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Polyribonucleotide nucleotidyltransferase, putative; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.956 |
| hfq | ptsG | SAOUHSC_01281 | SAOUHSC_00155 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport. | 0.710 |
| hfq | rho | SAOUHSC_01281 | SAOUHSC_02362 | Host factor 1 protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.769 |
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