| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABD29748.1 | cvfB | SAOUHSC_00610 | SAOUHSC_01391 | Conserved hypothetical protein. | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | 0.513 |
| ABD30487.1 | cvfB | SAOUHSC_01392 | SAOUHSC_01391 | ABC transporter, ATP-binding protein, putative. | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | 0.793 |
| cvfB | ABD29748.1 | SAOUHSC_01391 | SAOUHSC_00610 | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | Conserved hypothetical protein. | 0.513 |
| cvfB | ABD30487.1 | SAOUHSC_01391 | SAOUHSC_01392 | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | ABC transporter, ATP-binding protein, putative. | 0.793 |
| cvfB | cvfC | SAOUHSC_01391 | SAOUHSC_01437 | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | Conserved hypothetical protein; Required for hemolysin production. Contributes to virulence in both silkworm-infection model and mice. | 0.618 |
| cvfB | lspA | SAOUHSC_01391 | SAOUHSC_01162 | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.616 |
| cvfB | pyk | SAOUHSC_01391 | SAOUHSC_01806 | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.431 |
| cvfB | rny | SAOUHSC_01391 | SAOUHSC_01263 | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay (By similarity). In vitro, catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'- cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'-terminal of RNA. Activates sarZ and agr operon resulting in the expression of virulence genes such as hemolysin, DNase and protease. Contributes to virulence in both silkworm-infection model and mice. | 0.447 |
| cvfC | cvfB | SAOUHSC_01437 | SAOUHSC_01391 | Conserved hypothetical protein; Required for hemolysin production. Contributes to virulence in both silkworm-infection model and mice. | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | 0.618 |
| cvfC | rny | SAOUHSC_01437 | SAOUHSC_01263 | Conserved hypothetical protein; Required for hemolysin production. Contributes to virulence in both silkworm-infection model and mice. | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay (By similarity). In vitro, catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'- cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'-terminal of RNA. Activates sarZ and agr operon resulting in the expression of virulence genes such as hemolysin, DNase and protease. Contributes to virulence in both silkworm-infection model and mice. | 0.460 |
| lspA | cvfB | SAOUHSC_01162 | SAOUHSC_01391 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | 0.616 |
| lspA | pyk | SAOUHSC_01162 | SAOUHSC_01806 | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.489 |
| pyk | cvfB | SAOUHSC_01806 | SAOUHSC_01391 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | 0.431 |
| pyk | lspA | SAOUHSC_01806 | SAOUHSC_01162 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.489 |
| rny | cvfB | SAOUHSC_01263 | SAOUHSC_01391 | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay (By similarity). In vitro, catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'- cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'-terminal of RNA. Activates sarZ and agr operon resulting in the expression of virulence genes such as hemolysin, DNase and protease. Contributes to virulence in both silkworm-infection model and mice. | Conserved hypothetical protein; Contributes to the expression of virulence factors and to pathogenicity via both agr-dependent and agr-independent pathways. Involved in the production of hemolysin, DNase, protease and protein A. Contributes to virulence in silkworm-infection model and murine model of systemic infection. | 0.447 |
| rny | cvfC | SAOUHSC_01263 | SAOUHSC_01437 | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay (By similarity). In vitro, catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'- cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'-terminal of RNA. Activates sarZ and agr operon resulting in the expression of virulence genes such as hemolysin, DNase and protease. Contributes to virulence in both silkworm-infection model and mice. | Conserved hypothetical protein; Required for hemolysin production. Contributes to virulence in both silkworm-infection model and mice. | 0.460 |
