| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABD29287.1 | rnz | SAOUHSC_00106 | SAOUHSC_01598 | Conserved hypothetical protein. | AtsA/ElaC family protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.850 |
| ABD30679.1 | rnz | SAOUHSC_01600 | SAOUHSC_01598 | Conserved hypothetical protein. | AtsA/ElaC family protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.626 |
| ABD30679.1 | zwf | SAOUHSC_01600 | SAOUHSC_01599 | Conserved hypothetical protein. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.736 |
| polC | rnr | SAOUHSC_01241 | SAOUHSC_00803 | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Ribonuclease R, putative; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.531 |
| polC | rnz | SAOUHSC_01241 | SAOUHSC_01598 | DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | AtsA/ElaC family protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.563 |
| rnc | rnhB | SAOUHSC_01203 | SAOUHSC_01215 | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.595 |
| rnc | rnj1 | SAOUHSC_01203 | SAOUHSC_01035 | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit has the exonuclease activity. | 0.654 |
| rnc | rnj2 | SAOUHSC_01203 | SAOUHSC_01252 | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit probably plays a structural rather than enzymatic role as mutation of its putative active site gives no phenotype, and its deletion is partially complemented by inactive RNase J1. | 0.587 |
| rnc | rnr | SAOUHSC_01203 | SAOUHSC_00803 | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | Ribonuclease R, putative; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.644 |
| rnc | rny | SAOUHSC_01203 | SAOUHSC_01263 | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay (By similarity). In vitro, catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'- cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'-terminal of RNA. Activates sarZ and agr operon resulting in the expression of virulence genes such as hemolysin, DNase and protease. Contributes to virulence in both silkworm-infection model and mice. | 0.786 |
| rnc | rnz | SAOUHSC_01203 | SAOUHSC_01598 | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | AtsA/ElaC family protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.534 |
| rnhB | rnc | SAOUHSC_01215 | SAOUHSC_01203 | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.595 |
| rnhB | rnj1 | SAOUHSC_01215 | SAOUHSC_01035 | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit has the exonuclease activity. | 0.424 |
| rnhB | rnj2 | SAOUHSC_01215 | SAOUHSC_01252 | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit probably plays a structural rather than enzymatic role as mutation of its putative active site gives no phenotype, and its deletion is partially complemented by inactive RNase J1. | 0.423 |
| rnhB | rnr | SAOUHSC_01215 | SAOUHSC_00803 | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Ribonuclease R, putative; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.566 |
| rnhB | rny | SAOUHSC_01215 | SAOUHSC_01263 | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay (By similarity). In vitro, catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'- cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'-terminal of RNA. Activates sarZ and agr operon resulting in the expression of virulence genes such as hemolysin, DNase and protease. Contributes to virulence in both silkworm-infection model and mice. | 0.574 |
| rnhB | rnz | SAOUHSC_01215 | SAOUHSC_01598 | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | AtsA/ElaC family protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.534 |
| rnj1 | rnc | SAOUHSC_01035 | SAOUHSC_01203 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit has the exonuclease activity. | Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.654 |
| rnj1 | rnhB | SAOUHSC_01035 | SAOUHSC_01215 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit has the exonuclease activity. | Conserved hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.424 |
| rnj1 | rnj2 | SAOUHSC_01035 | SAOUHSC_01252 | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit has the exonuclease activity. | Conserved hypothetical protein; An RNase that has 5'-3' exonuclease and endonuclease activity, with the exonuclease activity probably being most important in vivo. Involved in maturation of 16S rRNA, rnpB (the RNA component of RNase P) maturation and degradation, and mRNA maturation and/or decay. This subunit probably plays a structural rather than enzymatic role as mutation of its putative active site gives no phenotype, and its deletion is partially complemented by inactive RNase J1. | 0.939 |