STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD30692.12-oxoisovalerate dehydrogenase, E1 component, alpha subunit, putative. (330 aa)    
Predicted Functional Partners:
ABD30690.1
2-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase, putative.
 
 0.999
ABD30691.1
2-oxoisovalerate dehydrogenase, E1 component, beta subunit, putative.
 0.999
ABD30161.1
Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase beta subunit, putative.
 0.998
ABD30693.1
Dihydrolipoamide dehydrogenase.
 
 
 0.997
ABD30163.1
Dihydrolipoamide dehydrogenase.
 
 
 0.995
ABD29684.1
Branched-chain amino acid aminotransferase.
   
 
 0.968
ABD30162.1
Dihydrolipoamide S-acetyltransferase component of pyruvate dehydrogenase complex E2, putative.
 
 0.950
odhB
2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.923
pflB
Formate acetyltransferase; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
   
 
 0.908
tdcB
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). Belongs to the serine/thre [...]
     
 0.887
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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