Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABD30722.1Glucokinase, putative. (328 aa)    
Predicted Functional Partners:
ptsG
PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
  
 0.988
glcB
PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).
  
 0.988
ABD29386.1
PTS system, glucose-specific IIBC component, putative.
  
 0.983
pgi
Glucose-6-phosphate isomerase.
 
  
 0.950
pgcA
Conserved hypothetical protein; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate (Probable). This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Belongs to the phosphohexose mutase family.
 
 
 0.943
ABD31624.1
Aldose 1-epimerase precursor, putative.
 
  
 0.929
ABD29411.1
6-phospho-beta-glucosidase, putative; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.911
ABD30522.1
Phosphotransferase system enzyme IIA, putative.
   
 
 0.903
ABD30723.1
Conserved hypothetical protein.
  
    0.864
ABD30720.1
Conserved hypothetical protein.
       0.856
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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