Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABD30800.1Conserved hypothetical protein. (380 aa)    
Predicted Functional Partners:
ABD29976.1
Conserved hypothetical protein.
 
 0.980
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.975
ABD31559.1
Conserved hypothetical protein.
   
 0.961
ABD30893.1
Conserved hypothetical protein.
  
  
 
0.916
ABD29224.1
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 
 0.903
mnmA
tRNA methyl transferase, putative; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.755
ABD30799.1
(5-methylaminomethyl-2-thiouridylate)- methyltransferase.
  
  
 0.755
ABD31309.1
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 
 0.715
ABD30002.1
Conserved hypothetical protein; Belongs to the HesB/IscA family.
 
 
 0.711
dnaK
DNAk protein, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.701
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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