| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABD30261.1 | apt | SAOUHSC_01152 | SAOUHSC_01743 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.901 |
| ABD30261.1 | deoD | SAOUHSC_01152 | SAOUHSC_00097 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Purine nucleoside phosphorylase. | 0.900 |
| ABD30261.1 | deoD-2 | SAOUHSC_01152 | SAOUHSC_02380 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Purine nucleoside phosphorylase. | 0.900 |
| ABD30815.1 | apt | SAOUHSC_01744 | SAOUHSC_01743 | Conserved hypothetical protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.856 |
| ABD30815.1 | hisF | SAOUHSC_01744 | SAOUHSC_03008 | Conserved hypothetical protein. | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.710 |
| adk | apt | SAOUHSC_02490 | SAOUHSC_01743 | Adenylate kinase, putative; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.922 |
| adk | purA | SAOUHSC_02490 | SAOUHSC_00019 | Adenylate kinase, putative; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.695 |
| adk | purB | SAOUHSC_02490 | SAOUHSC_02126 | Adenylate kinase, putative; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate lyase. | 0.945 |
| adk | purH | SAOUHSC_02490 | SAOUHSC_01017 | Adenylate kinase, putative; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.445 |
| apt | ABD30261.1 | SAOUHSC_01743 | SAOUHSC_01152 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.901 |
| apt | ABD30815.1 | SAOUHSC_01743 | SAOUHSC_01744 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein. | 0.856 |
| apt | adk | SAOUHSC_01743 | SAOUHSC_02490 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylate kinase, putative; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.922 |
| apt | deoD | SAOUHSC_01743 | SAOUHSC_00097 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase. | 0.909 |
| apt | deoD-2 | SAOUHSC_01743 | SAOUHSC_02380 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase. | 0.909 |
| apt | hisF | SAOUHSC_01743 | SAOUHSC_03008 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.868 |
| apt | hisH | SAOUHSC_01743 | SAOUHSC_03010 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Imidazole glycerol phosphate synthase, subunit H (hisH), putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.802 |
| apt | purA | SAOUHSC_01743 | SAOUHSC_00019 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.767 |
| apt | purB | SAOUHSC_01743 | SAOUHSC_02126 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase. | 0.966 |
| apt | purH | SAOUHSC_01743 | SAOUHSC_01017 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.972 |
| deoD | ABD30261.1 | SAOUHSC_00097 | SAOUHSC_01152 | Purine nucleoside phosphorylase. | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.900 |
