Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (307 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.999
pgi
Glucose-6-phosphate isomerase.
  
 0.990
ABD31397.1
Conserved hypothetical protein.
 
 
 0.968
fda
Fructose-bisphosphate aldolase class-I, putative.
  
 0.939
ABD30964.1
Conserved hypothetical protein.
   
 0.937
fbp
Conserved hypothetical protein.
     
 0.936
ABD29840.1
Fructose 1-phosphate kinase, putative; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.935
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.929
ABD30434.1
Transketolase; Belongs to the transketolase family.
  
 0.928
mtlD
Mannitol-1-phosphate 5-dehydrogenase, putative.
    
 0.922
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (18%) [HD]