Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABD30901.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (534 aa)    
Predicted Functional Partners:
ABD30900.1
Conserved hypothetical protein.
 
  
 0.920
ABD29526.1
Phosphoglycerate mutase family protein; Belongs to the phosphoglycerate mutase family.
  
 
  0.908
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.902
gpmA
Phosphoglycerate mutase, putative; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.902
ABD30903.1
Conserved hypothetical protein.
 
   
 0.718
glyA
Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.715
hisF
Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.715
ABD29507.1
Conserved hypothetical protein.
  
 
 0.706
ABD30899.1
Conserved hypothetical protein.
       0.689
ABD29294.1
Alcohol dehydrogenase, iron-containing, putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.681
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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