Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABD30908.1Transglycosylase domain protein. (301 aa)    
Predicted Functional Partners:
ABD30255.1
Penicillin-binding protein 1.
 
 
 0.973
ABD30728.1
Penicillin-binding protein 3.
  
 
 0.967
mgt
Transglycosylase domain protein; Peptidoglycan polymerase that catalyzes glycan chain elongation using lipid-linked disaccharide-pentapeptide as the substrate.
  
  
 
0.928
ABD29781.1
Penicillin-binding protein 4, putative; Belongs to the peptidase S11 family.
   
 
 0.926
ABD30552.1
Penicillin-binding protein 2.
  
  
 
0.925
gpsB
Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.871
ABD30180.1
Conserved hypothetical protein; Belongs to the SEDS family.
  
 
 
 0.739
ABD31353.1
Conserved hypothetical protein; Belongs to the SEDS family.
  
 
 
 0.719
ftsA
Cell division protein, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
  
   
 0.661
ABD31368.1
Bacteriophage L54a, single-stranded DNA binding protein.
 
   
 0.630
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (18%) [HD]