STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD30923.1Conserved hypothetical protein; Belongs to the FtsK/SpoIIIE/SftA family. (1274 aa)    
Predicted Functional Partners:
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.881
ABD30924.1
Conserved hypothetical protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.832
ABD30925.1
Conserved hypothetical protein; Belongs to the UPF0354 family.
       0.796
ABD30921.1
Conserved hypothetical protein.
  
    0.748
ABD29510.1
Chromosome partioning protein, ParB family, putative; Belongs to the ParB family.
  
  
 0.747
ABD32032.1
Conserved hypothetical protein; Belongs to the ParB family.
  
  
 0.720
ABD30920.1
Conserved hypothetical protein.
       0.689
esxA
Conserved hypothetical protein; Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion (By similarity). Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity (By similarity).
   
 
 0.685
ABD30927.1
Conserved hypothetical protein.
       0.669
ABD29726.1
Conserved hypothetical protein.
   
 
 0.667
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.