Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABD30943.1Conserved hypothetical protein. (187 aa)    
Predicted Functional Partners:
ABD30942.1
Conserved hypothetical protein.
 
    0.930
ABD29225.1
Conserved hypothetical protein.
    
   0.768
mraZ
Conserved hypothetical protein; Belongs to the MraZ family.
  
  
 0.751
ABD30941.1
Conserved hypothetical protein.
  
    0.723
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.640
ABD30939.1
Conserved hypothetical protein.
   
   0.634
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
    0.586
rpsP
Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
 
 0.492
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.490
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.486
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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